Tag Archives: gluten sensitivity

Move over gluten; new kid on the wheat sensitivity block

WheatTurns out gluten isn’t the only culprit when it comes to an immune reaction to wheat.

New research suggests non-gluten proteins are also a source of those immune reactions to wheat.

Wheat proteins called ATIs also trigger reactions

The new suspects are a family of proteins called amylase-trypsin inhibitors, or ATIs. While they make up only four percent of the proteins in wheat, ATIs can trigger powerful immune reactions that can spread from the gut to other tissues in the body, such as the lymph nodes, kidneys, spleen, and even the brain.

ATIs are also shown to inflame pre-existing chronic conditions, including multiple sclerosis, asthma, rheumatoid arthritis, non-alcohol fatty liver disease, lupus, and inflammatory bowel disease.

And, ultimately, ATIs contribute to the development of gluten sensitivity.

At this time, it’s not entirely clear how much of a role ATI proteins play compared to gluten. We know from the work of Aristo Vojdani, PhD that people with symptoms of gluten sensitivity have been shown to react to several different types of gluten, as well as lectins and agglutinin.

The evolution of understanding wheat sensitivity

It used to be celiac disease was the only recognized immune reaction to wheat. Celiac disease is an autoimmune condition that affects a small percent of the population and requires medically invasive diagnostic criteria.

Only more recently has mainstream medicine begun to accept non-celiac gluten sensitivity. Newer research, the sheer volume of gluten-sensitive patients, and the explosion of the gluten-free market has made gluten sensitivity impossible to deny.

For decades patients who tested negative for celiac disease or even gluten sensitivity (standard testing is severely limited) have been told “It’s all in your head.” Today, the scientific legitimacy of an immune reaction to wheat is growing.

Likewise, a growing number of doctors are more willing to offer a diagnosis of gluten sensitivity and effective treatment strategies.

Gluten reactions occur in brain and elsewhere

Symptoms of gluten sensitivity can include digestive issues such as abdominal pain and symptoms similar to irritable bowel syndrome (IBS). However, common symptoms not related to the gut include headaches, joint pain, eczema, brain fog, and a number of dysfunctions related to the brain and nervous system.

These symptoms improve quickly on a gluten-free diet for many.

Research on wheat immune sensitivity continues

Research continues and in the future, it may be your doctor recommends an “ATI-free” diet instead of a gluten-free diet for wheat sensitivity.

Either way, if you react to gluten, avoiding it is the best choice for your long-term health.

If you have concerns about reactions to gluten, contact me. Functional nutrition has effective protocols to assess and manage gluten sensitivity.

Scientists confirm gluten sensitivity is a real thing

gluten wordResearch has confirmed what many people have long known: Gluten sensitivity is a real thing.

A Columbia University Medical Center study found gluten sensitivity is not an imagined condition, as many seem to think these days, and that celiac disease or a wheat allergy are not required to react to gluten.

Although people with gluten sensitivity may not demonstrate classic symptoms or lab markers of celiac disease, gluten nevertheless causes an acute immune response in gluten sensitive people.

Symptoms of gluten sensitivity vary widely and often include fatigue, brain fog, memory problems, mood imbalances, joint pain, skin eruptions, respiratory issues, and worsening of existing health conditions.

Gluten sensitivity different than celiac disease

In celiac disease, the immune response to gluten happens primarily in the small intestine.

With gluten sensitivity, however, the immune response is systemic, meaning the inflammatory cells travel in the bloodstream throughout the body. This explains why symptoms vary so widely.

Researchers found that six months on a gluten-free diet normalized the immune response and significantly improved patient symptoms.

Gluten sensitivity awareness crucial for patients

Studies like this are important to help educate doctors that gluten sensitivity can cause chronic health problems.

Many doctors still believe that only celiac disease is to blame for a reaction to gluten. Because gluten sensitivity is largely dismissed and conventional testing for it is so inadequate, many patients unnecessarily suffer from undiagnosed gluten sensitivity.

Gluten linked to autoimmunity and brain disorders

What’s worse, gluten is linked to many autoimmune diseases. An autoimmune disease is a condition in which the immune system attacks and destroys tissue in the body. Common autoimmune diseases include Hashimoto’s hypothyroidism, multiple sclerosis, rheumatoid arthritis, and type 1 diabetes.

However, the tissue most commonly attacked in response to gluten sensitivity is neurological tissue.

In other words, your undiagnosed gluten sensitivity could be destroying your brain. This is why gluten causes brain-based disorders in many people.

Gluten sensitivity more common than celiac

Celiac disease was long thought to affect about 1 percent of the population, but newer research shows rates have gone up 700 percent in the last 50 years.

Also, numbers are likely even higher because testing for celiac disease is extremely stringent and outdated. (Diagnostic criteria were developed in Europe, where a celiac diagnosis qualifies one for disability payments.)

Estimates for the rate of gluten sensitivity range from 6 percent of the population to considerably higher—a randomized population sample of 500 people conducted by immunologist Aristo Vojdani, PhD found one in three people had gluten sensitivity.

Proper testing and strict gluten-free diet are vital

Most testing for gluten sensitivity is inaccurate as people can react to at least 12 different compounds in gluten. Standard tests only screen for one, alpha gliadin.

Also, many people have cross reactions to gluten, meaning they respond to other foods they eat as if it were gluten. Dairy is one of the most common of these. It’s important to test for cross-reactive foods and remove them from the diet along with gluten.

It’s also vital to strictly adhere to a gluten-free diet as the occasional cheat can keep inflammation high and chances at symptom recovery low.

Ask me for information and advice on the latest in testing for gluten sensitivity.